CBD Reduces Joint Inflammation, Synovial Angiogenesis and Bone Destruction in a Rheumatoid Arthritis Ku Model (Phytomedicine)

A study published in Phytomedicine found that CBD reduced joint inflammation, aberrant synovial angiogenesis and bone destruction in a rheumatoid arthritis Ku model. Researchers at Hunan University of Chinese Medicine examined whether inhibiting synovial angiogenesis could delay disease progression and report that CBD does not act primarily by directly suppressing synovial fibroblast hyperactivity; rather, it blocks pro‑angiogenic signaling between synovial cells and endothelial cells. These findings highlight CBD’s potential as a disease‑modifying, anti‑angiogenic therapeutic approach for rheumatoid arthritis.

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